This project has been made possible in part by a grant from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation.
The Harvard Center for Biological Imaging (HCBI) was opened May 17, 2010 and is one of the most innovative biological imaging centers in the world.
In order to ensure investigators always have access to the latest and best technologies, the HCBI was designed to be an “Evergreen” microscopy facility. Imaging systems at the HCBI are leased rather than purchased and replaced every 2-3 years. This ensures that the facility remains relevant and is never in possession of outdated equipment.
Currently, the HCBI contains 18 microscopes and high-end processing stations including:
Both lighsheet and upright confocal/multiphoton systems can be used with live water immersion or cleared tissue immersion objectives.
The facility also features wet lab space, eukaryotic and prokaryotic incubation, and access to nearby animal care facilities for a wide range of species.
Website: https://hcbi.fas.harvard.edu/
Aspects related to user access
Quality management
Core facility management
Software tools
Image data storage and analysis
Hands-on: see instruments at https://hcbi.fas.harvard.edu/equipment
Biweekly Lunch and Learn seminars during the Fall semester and Summer
Two day intensive microscopy course during January winter session
Hands on tissue clearing workshop
Data analysis workshops at various times of the year
Departmental weekly seminars, including Cell Dynamics (Systems Biology), Molecular and Cellular Biology, Center for Brain Science (Neuroscience), and Chemistry and Chemical Biology that are open to guests
Facility manager
Imaging specialist
1-2 weeks
