UC Berkeley - CRL Molecular Imaging Center (MIC)

The CRL Molecular Imaging Center (MIC) is a shared light microscopy resource specializing in state-of-the-art laser-based fluorescence imaging techniques.

The MIC offers training and expertise in 20 different microscope systems, including live cell and in vivo imaging, laser
scanning (LSM) and spinning disk (SDC) confocal, multi-photon (2p), fluorescent lifetime imaging (FLIM), light-sheet microscopy (SPIM), super resolution (Airyscan), slide scanning and patterned illumination for optogenetic manipulation and readout.

The MIC provides offline computer analysis workstations for image processing, visualization and analysis, including GPU workstations.
The MIC is accessible to all researchers across the UC Berkeley campus, as well as non-UCB, and non-academic laboratories and companies.

In conjunction with the Vision Sciences core program, the MIC also offers expertise in designing and building custom optical and electrical systems with an emphasis in neurophysiology, as well as quantitative image processing. The Vision Sciences program has a wide array of modified and custom built microscopy systems including:

● Two-photon tracking scanning laser opthalmoscope (TSLO)

● Custom two-photon laser scanning microscopes for simultaneous calcium imaging and optogenetics/optopharmacology and/or visual stimulation

● Simultaneous two-photon and infrared single-photon confocal microscope.

Websites: http://imaging.berkeley.edu; https://vision.berkeley.edu/faculty/core-grants-nei/core-grant-microscopic-imaging/